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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ABCA1
All Species:
22.42
Human Site:
Y2041
Identified Species:
44.85
UniProt:
O95477
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95477
NP_005493.2
2261
254286
Y2041
L
V
K
Y
G
E
K
Y
A
G
N
Y
S
G
G
Chimpanzee
Pan troglodytes
XP_001138040
2261
254230
Y2041
L
V
K
Y
G
E
K
Y
A
G
N
Y
S
G
G
Rhesus Macaque
Macaca mulatta
XP_001106713
1081
120445
P868
A
S
F
V
F
K
I
P
S
T
A
Y
V
V
L
Dog
Lupus familis
XP_538773
2261
253895
Y2041
L
V
K
Y
G
E
K
Y
A
G
N
Y
S
G
G
Cat
Felis silvestris
Mouse
Mus musculus
P41233
2261
253955
Y2041
L
V
K
Y
G
E
K
Y
A
S
N
Y
S
G
G
Rat
Rattus norvegicus
Q7TNJ2
2170
237702
P1947
L
P
S
Y
A
D
R
P
A
G
T
Y
S
G
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516009
2266
254238
Y2046
L
L
K
Y
G
E
K
Y
A
G
N
Y
S
G
G
Chicken
Gallus gallus
NP_989476
2260
254054
Y2040
L
V
K
Y
G
E
K
Y
A
G
N
Y
S
G
G
Frog
Xenopus laevis
NP_001089022
2363
267334
L2146
V
G
K
Y
A
D
N
L
A
G
T
Y
S
G
G
Zebra Danio
Brachydanio rerio
XP_683123
2330
265308
C2112
L
S
E
Y
A
G
N
C
A
G
T
Y
S
G
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34358
1704
191394
G1491
E
L
I
L
E
C
V
G
M
I
A
H
A
D
K
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q84M24
1882
209045
L1669
G
I
M
V
G
G
R
L
R
C
I
G
S
P
Q
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
47
94.9
N.A.
95
50.8
N.A.
89.1
85.4
49.8
51.1
N.A.
N.A.
N.A.
24.9
N.A.
Protein Similarity:
100
99.7
47.5
97.6
N.A.
97.3
67.4
N.A.
94.6
92.6
66.8
67.8
N.A.
N.A.
N.A.
43
N.A.
P-Site Identity:
100
100
6.6
100
N.A.
93.3
53.3
N.A.
93.3
100
53.3
53.3
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
100
100
20
100
N.A.
93.3
66.6
N.A.
100
100
66.6
60
N.A.
N.A.
N.A.
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
27.4
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
43.8
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
0
25
0
0
0
75
0
17
0
9
0
0
% A
% Cys:
0
0
0
0
0
9
0
9
0
9
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
17
0
0
0
0
0
0
0
9
0
% D
% Glu:
9
0
9
0
9
50
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
9
0
9
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
9
9
0
0
59
17
0
9
0
67
0
9
0
75
75
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% H
% Ile:
0
9
9
0
0
0
9
0
0
9
9
0
0
0
0
% I
% Lys:
0
0
59
0
0
9
50
0
0
0
0
0
0
0
9
% K
% Leu:
67
17
0
9
0
0
0
17
0
0
0
0
0
0
9
% L
% Met:
0
0
9
0
0
0
0
0
9
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
17
0
0
0
50
0
0
0
0
% N
% Pro:
0
9
0
0
0
0
0
17
0
0
0
0
0
9
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% Q
% Arg:
0
0
0
0
0
0
17
0
9
0
0
0
0
0
0
% R
% Ser:
0
17
9
0
0
0
0
0
9
9
0
0
84
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
9
25
0
0
0
0
% T
% Val:
9
42
0
17
0
0
9
0
0
0
0
0
9
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
75
0
0
0
50
0
0
0
84
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _